Because of the mutual connections in a locally developed ecosystem, the locally evolved relationships are extremely important. The place is a breeding ground. The mutual symbiotic adjustments of the symbionts in a holobiont are disturbed when even one species is removed.
Ultimately, the entire web of relationships is carried by microbes. For example, in humans, communication between the brain and the stomach is just as fundamental to capabilities and behavior as the brain. These stomach-brain connections apply to all mammals. One of the most famous researchers in this area, Emeran Mayer, writes in The Mind-Gut Connection: How the Hidden Conversation Within Our Bodies Impacts Our Moods, Our Choices, and Our Overall Health (2016), that the gut and the inhabitants of the Gut, the microbes, think for the brain. That is why he calls the bowels the ‘second brain’. The bacteria in the gastrointestinal tract play a central role: the presence of certain types of bacteria and their products have a major influence on the willingness to take risks, on thought processes, and on moods such as apathy and depression. In addition, the digestion of foods is largely provided by intestinal bacteria, as is the stimulation of the immune system. This is why the microbiome is a second brain. Michiel Korthals
We are all Interconnected even with the Universe 
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